![]() Furthermore, it appears to be reduced in the cleavage furrow. During cytokinesis, dynacortin is found in the cortex and is somewhat enriched at the poles. ![]() Dynacortin is localized partly to the cell cortex and becomes enriched in protrusive regions, a localization pattern that is similar to coronin and partly dependent on RacE. The cortexillin I locus and transcript were found to be disrupted in the strain, identifying it as the affected gene. These include the cleavage furrow protein cortexillin I, a novel protein we named dynacortin, an ezrin-radixin-moesin-family protein, and coronin. Isolates of four different genes were recovered as modifiers of this strain's cytokinesis defect. ![]() Chemically mutagenized cells were screened for cytokinesis-deficient mutants and one mutant was subjected to library complementation. We have developed a system for performing interaction genetics in Dictyostelium discoideum that uses a cDNA library complementation/multicopy suppression strategy.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |